#3250 RENAL HAEMODYNAMIC PARAMETERS IN DIABETIC NEPHROPATHY

Abstract Background and Aims Diabetic nephropathy is the leading cause of chronic kidney disease in modern world. Timely diagnosis paramount importance, especially after recent introduction novel therapies. The presence an already altered renal haemodynamic profile was investigated all patients referred with suspected diabetic nephropathy, upon their initial presentation to our department. Method During past seven years, from January 2015 December 2022, 578 were Renal Department for ultrasound assessment. Additionally standard assessment, they underwent triplex examination. (DN) diagnosed 149 patients. A group estimated GFR> 60 ml/min, without randomly selected same pull comparison reasons (control group). haemodynamics including arteries, aorta intrarenal resistive indexes (RI) both kidneys, glomerular filtration rate (CKDEPI) 24h albuminuria, evaluated Results mean age 72.5 ±10.4 vs 65.8 ±6.9 DN control respectively. length comparable groups, diameter left 10.61 ±1.28 vs. 10.59 ±1.44 cm right 10.53 ±1.38 9.85 ±2.89 GFR significantly lower group, 42.1±23.6 82.7 ±11.3 ml/min (p<0.05). Both arteries presented higher velocity values 53.4 ±22.2 21.7 ±28.9 cm/sec (p<0.0001) 52.4 ±23.9 24.8 ±32.3 (p<0.0001), artery. showed RI above upper normal limit 0.70, being at time compared 0.73 ±0.06 0.61 ±0.17 0.72 0.59 ±0.20 Conclusion increased artery has not been described earlier best knowledge. It represents a new finding that mainly attributed arteriopathy. Evaluation using ultrasound, non – invasive, readily available, inexpensive When performed patient presentation, constitutes invaluable tool, timely assisting treatment